The Role of Antioxidant to Prevent Free Radicals in The Body

Siti Thomas Zulaikhah

Abstract


Antioxidants are compounds capable of counteracting or reducing the negative effects of oxidants in the body. Antioxidants work by donating an electron to an oxidant compound so that the activity of the oxidant compound can be inhibited. Antioxidants are grouped into two categories, namelu enzyme and non-enzyme antioxidants. Antioxidant enzymes such as superoxide dismutase (SOD) enzyme, catalase (CAT), and glutathione peroxidase (GPx), Non-enzyme antioxidants are found in vegetables and fruits, including reduced glutathione (GSH), vitamin C, E, β-Carotene, flavonoids, isoflavones, flavones, anthocyanins, catechins, and isocatechins, as well as lipoic acid. Low antioxidant enzymes can be used as a marker of high levels of free radicals in the body. The following review aims to provide an overview of the role of antioxidants in preventing the formation of free radicals in the body.

Keywords


Antioxidants, free radicals, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx)

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DOI: http://dx.doi.org/10.30659/sainsmed.v8i1.262

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• pISSN: 2085-1545 • eISSN: 2339-093X 

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Based on a work at http://sainsmedika.fkunissula.ac.id/index.php/sainsmedika

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